Table 3.
Applicability of different model formalisms analyzed into different biological situations.
| Modeling framework | Intracellular circuits | Cell–cell interactions | Host-pathogen interactions | Local tissue interaction | Systemic infection/inflammation |
|---|---|---|---|---|---|
| ABM | |||||
| Boolean | |||||
| ODE | |||||
| Stochastic | |||||
| Fuzzy Logic |
Applicability: This table presents an illustrative guidance to select the best modeling framework to the biological scale of interest. Depending on the scale the applicability of the different frameworks can be poor (black) possible (gray) or appropriate (white).