Table 1.
Clinical features of patients
| Patient | Sex | Age at the onset (m) | Age (m) | Developmental status | Etiology | Epilepsy syndrome | MRI results | Comments |
|---|---|---|---|---|---|---|---|---|
| 1 | F | 7 | 63 | Moderate delay | Genetic anomaly | Absence- tonic-GTC | Normal | |
| 2 | M | 21 | 78 | Severe delay | Encephalitis | Myoclonic-tonic | Diffuse atrophy | |
| 3 | M | 3 | 22 | Severe delay | Prematurityhypoxic-ischemic encephalopathy | Myoclonic-tonic-GTC | Hypoxic-ischemic change PVL | |
| 4 | M | 6 | 36 | Severe delay | Unknown | Myoclonic | Normal | History of West syndrome |
| 5 | M | 30 | 92 | Severe delay | Hypoxic-ischemic encephalopathy | Myoclonic-absence-tonic | Mild Hypoxic-ischemic change PVL-atrophy |
|
| 6 | M | 24 | 57 | Severe delay | Hypoxic-ischemic encephalopathy | Myoclonic-tonic | Hypoxic-ischemic change | |
| 7 | M | 9 | 35 | Moderate MR | Cerebral dysgenesis | Myoclonic-GTC | Pachygyria | History of West syndrome |
| 8 | F | 11 | 67 | Severe delay | Unknown | Myoclonic-GTC-tonic | Mild atrophy | |
| 9 | M | 8 | 38 | Moderate delay | Unknown | Myoclonic-atonic | Normal | History of West syndrome |
| 10 | F | 7 | 44 | Severe delay | Cerebral dysgenesis | Atonic-tonic-Myoclonic- | Pachygyria | |
| 11 | F | 3 | 74 | Moderate delay | Hypoxic-ischemic encephalopathy | Myoclonic-GTC | Hypoxic-ischemic change PVL | |
| 12 | M | 1 | 28 | Severe delay | Syndromic anomaly | Tonic-GTC-Atonic-myoclonic | Normal | |
| 13 | F | 3 | 39 | Moderate delay | Unkown | Myoclonic-absence-GTC | Mild atrophy | |
| 14 | M | 1 | 48 | Severe delay | Unknown | Myoclonic-tonic-GTC | Atrophy | |
| 15 | F | 7 | 112 | Moderate delay | Genetic anomaly | Myoclonic –absence-partial | Normal | |
| 16 | M | 1 | 32 | Severe delay | Hypoxic-ischemic encephalopathy | Tonic-myoclonic | Hypoxic-ischemic change PVL |
|
| 17 | M | 20 | 45 | Severe delay | Cerebral dysgenesis Microcephaly |
Myoclonic | Polymicrogyria | |
| 18 | M | 8 | 27 | Moderate delay | Hypoxic-ischemic encephalopathy | Partial-GTC | Mild Hypoxic-ischemic change PVL |
|
| 19 | F | 5 | 94 | Moderate delay | Unknown | Myoclonic-tonic-GTC | Mild atrophy | |
| 20 | F | 1 | 48 | Severe delay | Cerebral dysgenesis | Myoclonic-tonic-absence | Cerebral dysgenesis | |
| 21 | M | 10 | 30 | Severe delay | Herpes encephalitis | MYOCLONIC-ATONIC-PARTIAL | Bilateral temporal encephalomalacia | Normal development before encephalitis |
| 22 | M | 8 | 67 | Moderate delay | Cerebral dysgenesis | Myoclonic-GTC- | Pachygyria polymicrogyria | |
| 23 | F | 5 | 56 | Severe delay | Genetic anomaly | Myoclonic-atonic | Normal | |
| 24 | F | 9 | 123 | Severe delay | Unknown | Myoclonic-atonic | Normal | |
| 25 | F | 18 | 108 | Severe delay | Genetic anomaly | Tonic-Atonic—GTC-absence | Normal |