TaqExo analysis of types
1a, 1b, 2 and 3 5′-UTR HCV DNA fragments.
(A) Alignment of DNA sequences corresponding to
nucleotides –31 to –274 of the 5′-UTR
of type 1a, 1b, 2 and 3 negative strand HCV RNAs (40). Major cleavage
sites are indicated by arrows. (B) TaqExo cleavage
products of type 1a, 1b, 2 and 3 DNAs shown in (A). M, size markers.
The sizes of major cleavage products of type 1b DNA are indicated
on the left.