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. 2017 Aug 30;8:1674. doi: 10.3389/fmicb.2017.01674

Table 1.

Anti-DENV activity of compounds and extracts derived from crude drugs.

Compound EC50a (μM) CC50b (μM) SIc
Hirsutine 1.9 >10 >5.3
Timosaponin-AIII 1.7 >10 >5.9

Extract EC50a (μg/mL) CC50b (μg/mL) SIc

Albizziae Cortex 2.9 >100 >34.5
Phellodendri Cortex 3.9 >100 >25.6
Arecae Semen 37.5 >100 >2.7

aHalf maximal effective concentration; EC50. bHalf maximal cytotoxicity concentration; CC50. cSelectivity index; SI = CC50/EC50.