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. 2017 Aug 30;10:275. doi: 10.3389/fnmol.2017.00275

Table 5.

Top 5 Networks identified by the Ingenuity® Pathway Analysis (IPA).

ID Molecules in network Score Focus molecules
1 26s Proteasome, ACKR1, Akt, ARR3, BCR (complex), BTG2, CD3, CDC25A, CITED2, Creb, CTTN, DUSP1, ERK, ERK1/2, FOS, GIPR, Histone h4, ICOSLG/LOC102723996, IgG1, Jnk, KHDRBS1, NFkB (complex), NR4A2, P38 MAPK, PDGF BB, PI3K (complex), SBSN, SIAH2, SPN, STAT5a/b, TCR, TICAM2, TRIB1, WNT6, XBP1 36 19
2 ACOX1, BCL2, Cd33, CD68, CD84, CDK9, CDKN1C, CEBPD, COL4A1, COPA, cytochrome C, DIO1, E2F3, GH1, Growth hormone, IGF1R, IGFBP5, IRS2, LIPE, LONP1, LPL, Mcpt8, MEDAG, MYBL1, MYBL2, NCL, NCSTN, NDUFS2, NIT1, PPM1B, PRKAR1A, PTTG1, RB1, STAG3, TXN 16 10
3 ADAMTS1, AGMAT, Cg, CNIH4, CYP17A1, DUSP10, EBI3, F2RL1, FSH, GAD1, GLI1, Histone h3, HMGA2, HPGD, IER3, IGFBP7, IL4, IL11, IMPDH1, KDM5B, KMT2D, LGALS3BP, LMNB1, POLM, PPOX, PTX3, RETN, RPS6KA3, SMARCA4, SNUPN, STAR, TBX15, Tpm4, TRIB1, WDSUB1 14 9
4 BCAR3, CDK11A, DIAPH3, ELK3, ENO1, ERK, ETS1, ETV4, GRHL2, HAS3, INF2, ITGA3, KIF23, LAMA3, MCIDAS, MKRN3, MYH6, MYL9, PERP, PHLDA1, PIK3R3, S100A7, S100A8, SCN9A, SEMA3B, SLC26A1, SLPI, SRF, TLR3, TNFAIP8, TP63, Tpm1, ULBP2, YY1, ZDHHC2 14 9
5 ARAF, ASPM, CAMK4, CAPN10, CBLN4, CCR7, CDK2AP1, CHRNA5, CPLX1, CTHRC1, DDC, DOCK1, EP300, FKBP1B, FOXO1, HNF4A, IKZF5, INSIG1, INTS13, IRS2, KIF1B, LIPE, LYL1, MED1, NKX3-1, NR1I3, NTN1, Proinsulin, RAB3A, RYR2, SERPINB2, SNCA, SREBF1, TAL1, TCF3 10 7