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. 2017 Jul 28;8(5):501–510. doi: 10.1111/1759-7714.12476

Figure 5.

Figure 5

HMGA2 was directly targeted and downregulated by miR‐195. (a) Diagram of HMGA2 3’ untranslated region (UTR)‐containing reporter construct. (b) Relative luciferase activity after the wild type or mutant reporter plasmids were co‐transfected with miR‐195 mimic or control. n.s., no significance. (c) Real time‐PCR analysis of HMGA2 messenger RNA (mRNA) expression and (d) Western blot analysis of HMGA2 protein expression in lung cancer cells transfected with miR‐195 mimic or inhibitor. * P < 0.05. GAPDH, glyceraldehyde 3‐phosphate dehydrogenase.