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Caspase-3-treated BLM retains helicase activity. Helicase assays were performed with either caspase 3-treated or mock-treated recombinant BLM as described in Materials and Methods. The amount of BLM included in each reaction ranged from 7.5 to 50 ng. Positions of the starting substrate and the unwound oligonucleotide product are indicated on the left.
