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. 2017 Aug 16;56(37):11166–11194. doi: 10.1002/anie.201702531

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© 2017 The Authors. Published by Wiley-VCH Verlag GmbH & Co. KGaA.

This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

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An actin filament tied in a knot by molecular tweezers.129 Tightening of the knot eventually causes the filament to break at the location of the knot. Adapted from Ref. 129 with permission from Springer Nature.