VWF multimers were classified as LMW (corresponding to bands 1–5 in VWFM analysis), IMW (bands 6–10) and HMV (bands ≥11). HMW bands that were not detected in normal plasma were defined as UL-VWFM. VWF, von Willebrand factor; LMW, low molecular weight; IMW, intermediate molecular weight; HMW, high molecular weight; UL-VWFM, unusually large von Willebrand factor multimers; ALF, acute liver failure; NP, normal plasma.