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. 2017 Aug 31;11:1179552217729343. doi: 10.1177/1179552217729343

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© The Author(s) 2017

This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (http://www.creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access page(https://us.sagepub.com/en-us/nam/open-access-at-sage).

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Figure 3. — Meta-regression of relationship between geographic location and colonic transit time in adults with functional constipation. Percentage of variance in transit time explained by geography = 57%, P = .04. Pairwise comparisons: Europe vs Asia, P = .04; Europe vs Americas, P = .02. Open circles represent values of individual studies where circle size is proportional to the study weight in the random-effects model. Thick lines represent the pooled mean in each group. Thin lines represent the 95% confidence interval of the pooled mean in each group.