Body weight, mass composition, and glucose tolerance. A: body weight of mice on chow diet. B: body weight curve on Western-type diet (WTD). C: body mass composition at the beginning (t0) and after 4-wk WTD feeding. D: change in mass due to WTD. E and F: plasma insulin and glucose after an overnight fast. G: hepatic content of glycogen after 4-h refeeding WTD. H and I: oral glucose tolerance test and area under the curve (AUC). Values are displayed as means ± SE; n = 7. For acylglycerols and cholesterol, values were averaged from two technical replicates. Statistical significance is represented as *P < 0.05, **P < 0.01 measured by one-way ANOVA. For B, we used ANOVA with repeated measures.