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. 2017 May 17;313(2):F522–F534. doi: 10.1152/ajprenal.00620.2016

Fig. 3.

Fig. 3.

Arg2 deficiency or arginase inhibition improve kidney function after IRI. WT and Arg2−/− mice were subjected to bilateral renal ischemia for 28 min, followed by reperfusion for 24 h (A and B). Mice were treated with vehicle or BEC 18 h before ischemia (C and D). Values are means ± SE for n = 6 mice in each group. *P < 0.05 and **P < 0.01 vs. sham. #P < 0.05 and ##P < 0.01 vs. vehicle-treated or WT IRI.