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Arginase inhibition does not improve kidney function after IRI in eNOS−/− mice. eNOS−/− mice were treated with BEC 18 h before being subjected to bilateral renal ischemia for 28 min, followed by reperfusion for 24 h. Shown are plasma BUN levels (A), creatinine levels (B), and kidney KIM-1 mRNA levels (C). Values are means ± SE for n = 6 mice in each group. *P < 0.01 vs. sham.
