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. 2017 May 17;313(2):F326–F338. doi: 10.1152/ajprenal.00039.2017

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Fig. 2. — The relative renal gene expression of the sodium transporters. Renal gene expression of Na⁺/H⁺ exchanger 3 (NHE3; A; *P < 0.01 vs. M/M; &P < 0.01 vs. M/M and F/M; @P < 0.05 vs. F/F). Protein levels showed the similar pattern as mRNA expression. Na⁺-K⁻-2Cl cotransporter 2 (NKCC2; B; *P < 0.01 vs. FC; #P < 0.01 vs. F/F); Na⁺-Cl⁻ cotransporter (NCC; C; *P < 0.01 vs. FC; #P < 0.01 vs. F/F; &P < 0.01 vs. F/M); and α (E)-, β (D)- and γ (F)-epithelial Na⁺ channels (ENaC) (*P < 0.01 vs. FC; #P < 0.01 vs. F/F;) of the transplanted kidneys at 4 wk after transplantation. Protein levels of NHE3 and NKCC2 showed the similar sex difference pattern as mRNA expression, respectively (donor/recipient; M, male, F, female; n = 6).

Fig. 2. — The relative renal gene expression of the sodium transporters. Renal gene expression of Na⁺/H⁺ exchanger 3 (NHE3; A; *P < 0.01 vs. M/M; &P < 0.01 vs. M/M and F/M; @P < 0.05 vs. F/F). Protein levels showed the similar pattern as mRNA expression. Na⁺-K⁻-2Cl cotransporter 2 (NKCC2; B; *P < 0.01 vs. FC; #P < 0.01 vs. F/F); Na⁺-Cl⁻ cotransporter (NCC; C; *P < 0.01 vs. FC; #P < 0.01 vs. F/F; &P < 0.01 vs. F/M); and α (E)-, β (D)- and γ (F)-epithelial Na⁺ channels (ENaC) (*P < 0.01 vs. FC; #P < 0.01 vs. F/F;) of the transplanted kidneys at 4 wk after transplantation. Protein levels of NHE3 and NKCC2 showed the similar sex difference pattern as mRNA expression, respectively (donor/recipient; M, male, F, female; n = 6).