Table 3.

Effect of COX2 KO on glomerular structure in Akita mice

	Podocytes per	VGlom	NV (P/Glom)	Podocytes per
	Glomerular Profile	(×105 µm3)	(×10−5/µm3)	Glomerulus
COX2+/+	8.14 ± 0.19	2.58 ± 0.09	22.6 ± 0.5	58.3 ± 1.7
(n = 5)
COX2−/−POD	7.82 ± 0.23	2.56 ± 0.06	22.6 ± 0.7	56.8 ± 1.7
(n = 5)
WT Akita	7.54 ± 0.20	3.35 ± 0.14†	18.1 ± 0.4‡	60.5 ± 1.4
(n = 16)
KO Akita	7.31 ± 0.19	3.20 ± 0.13*	18.4 ± 0.4§	55.5 ± 1.4
(n = 13)

Values are expressed as means ± SE.

^*P < 0.05, vs. nondiabetic COX2−/−.

^†P < 0.01, vs. nondiabetic COX2+/+.

^‡P < 0.001, vs. nondiabetic COX2+/+.

^§P < 0.001, vs. nondiabetic COX2−/−.