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Hypoxia-induced increases in force of pulmonary arterial rings isolated from WT (n = 12) and sEH-KO mice (n = 12) in the absence and presence of Nω-nitro-l-arginine methyl ester (l-NAME; A) or indomethacin (Indo; B). *Significant difference from their corresponding controls without inhibitors, P < 0.05. @Significant difference from WT, P < 0.05. #Significant difference from sEH-KO without Indo, P < 0.05.
