Table 1.

Radiofluorination conditions^[a]

Entry	PDFA (μmol)	S8 (μmol)	Cu	T (°C)	Yield (%)[b] (n = 3)
1	20	60	none	70	36±6
2	20	60	Cul	70	64 ±6
3	20	60	Cul	40	65±6
4	20	60	Cul	rt	3±2
5	30	90	Cul	40	72±6
6[c]	30	90	Cul	40	8±4

^[a]Reaction conditions: 10 μmol precursor, PDFA, S₈ and 10 μmol Cul in 400 μL MeCN;

^[b]radiochemical conversion yields and product identity were determined by radioTLC and radioHPLC, respectively;

^[c]1% Water was added in the reaction