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Xanthine oxidase (XO) inhibition does not impact changes in body weight, adiposity, or fasting glucose induced by Western diet (WD). A: body weight; B: body fat composition (%total body weight) by quantitative magnetic resonance (echoMRI-500); C: fasting plasma glucose concentration; D: plasma uric acid levels (samples obtained under anesthesia). *P < 0.05, control diet (CD) vs. WD; #P < 0.05, WD vs. WD-allopurinol (ALLO); n = 4–8 for all groups.
