Table 1.

Arterial blood gases, lactate, glucose, and insulin concentrations during HEC study

	Fasting (Basal)		Hyperinsulinemia
Parameter	Control (n = 8)	IUGR (n = 5)	Control (n = 8)	IUGR (n = 5)	P Value Group	P Value Period	P Value Interaction
pH	7.46 ± 0.01	7.43 ± 0.02	7.42 ± 0.01	7.38 ± 0.02	0.12	<0.01	0.85
$\mathrm{P}{\mathrm{a}}_{\mathrm{O}}{}_{{}_{\mathrm{2}}}$, mmHg	76.4 ± 2.8	72.8 ± 3.3	84.9 ± 2.8	74.6 ± 3.5	0.10	0.02	0.11
$\mathrm{P}{\mathrm{a}}_{\mathrm{C}\mathrm{O}}{}_{{}_{\mathrm{2}}}$, mmHg	39.8 ± 1.5	42.4 ± 1.7	41.2 ± 1.5	44.1 ± 1.8	0.23	0.06	0.76
O2 content, mM	6.1 ± 0.3	6.1 ± 0.4	6.0 ± 0.3	5.7 ± 0.4	0.74	0.03	0.22
Hematocrit, %	32.4 ± 1.7	34.1 ± 1.8	31.1 ± 1.7	32.4 ± 1.9	0.59	<0.01	0.45
Lactate, mM	1.01 ± 0.08a,b	1.09 ± 0.09a,b	0.84 ± 0.08b	1.27 ± 0.10a	0.02	0.95	0.05
Glucose, mmol/l	8.54 ± 0.52	8.02 ± 0.60	8.27 ± 0.52	8.51 ± 0.63	0.87	0.66	0.09
Insulin, µg/l	0.93 ± 0.37	0.75 ± 0.42	4.33 ± 0.37	3.54 ± 0.51	0.29	<0.01	0.46

Values are expressed as means ± SE; n, number of lambs. HEC, hyperinsulinemic-euglycemic clamp; IUGR, intrauterine growth restriction. Superscript letters denote differences for significant interactions between experimental group and period.