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. Author manuscript; available in PMC: 2018 Sep 1.
Published in final edited form as: Brain Lang. 2017 May 31;172:22–29. doi: 10.1016/j.bandl.2017.04.008

Figure 3.

Figure 3

GLI3 SNPs are associated with lower language performance. (a) Linkage disequilibrium map of the four GLI3 SNPs significantly associated with language performance. The minor allele of rs3801203 (b-c, p = 3.21 × 10−9) was associated with lower language composite score in older adults at risk for or with AD, with the exception of the SMC group. Means adjusted for age, sex, years of education, genotyping platform, handedness, and APOE ε4 status. Standard errors are displayed.

CN = cognitively normal; SMC = significant memory concern; EMCI = early mild cognitive impairment; LMCI = late mild cognitive impairment; AD = Alzheimer’s disease