Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2017 Aug 31;9:277. doi: 10.3389/fnagi.2017.00277

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2017 Caldeira, Cunha, Vaz, Falcão, Barateiro, Seixas, Fernandes and Brites.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

Amyloid-β (Aβ) peptide upregulates the expression of Toll-like receptor 2 (TLR2), TLR4 and fractalkine/CX3C chemokine receptor 1 (CX3CR1) in the reactive cultured microglia, but not in aged cells. Microglia that were kept in culture for 2 and 16 days in vitro (DIV) were treated with 1000 nM Aβ for 24 h. Expression of TLR2 (A), TLR4 (B) and CX3CR1 (C) was evaluated by Real-Time PCR. Results are expressed in graph bars as mean ± SEM. Cultures, n = 4 per group. Two-way ANOVA (Post hoc Bonferroni test): *p < 0.05 vs. respective non-treated Control; ^††p < 0.01 vs. 2 DIV cells; (A) DIV × Aβ interaction F_(5.29), p < 0.05.