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. 2017 Aug 31;8:219. doi: 10.3389/fendo.2017.00219

Table 5.

Dual energy X-ray absorptiometry bone parameters in men.

Age (yr) 40–44 (n = 25) 45–49 (n = 34) 50–54 (n = 29) 55–59 (n = 31) 60–64 (n = 27) 65–69 (n = 35) 70–74 (n = 30) 75+ (n = 28) β-Coefficient (95% CI) R2 Unadjusted p-value β-Coefficient (95% CI) R2 Adjusted p-value

Whole body
aBMD (g/cm2) 1.2 ± 0.1(n=24) 1.2 ± 0.1 1.2 ± 0.1 1.1 ± 0.1 1.1 ± 0.1 1.1 ± 0.1 1.1 ± 0.1(n=29) 1.1 ± 0.1(n=26) −0.003 (−0.004, −0.002) 0.13 <0.0001 −0.002 (−0.003, −0.0008) 0.34 <0.0001
BMC (g) 2,804 ± 433(n=24) 2,632 ± 358 2,739 ± 433 2,532 ± 374 2,442 ± 448 2,433 ± 366 2,335 ± 299(n=29) 2,279 ± 380(n=26) −13.3 (−17.4, −9.2) 0.15 <0.0001 −3.9 (−6.6, −1.1) 0.66 0.007
BA (cm2) 2,355 ± 200(n=24) 2,275 ± 212 2,321 ± 233 2,242 ± 217 2,210 ± 243 2,175 ± 215 2,171 ± 204(n=29) 2,087 ± 205(n=26) −6.2 (−8.5, −3.9) 0.11 <0.0001 −0.1 (−1.2, 1.0) 0.83 0.856
Spine
aBMD (g/cm2) 1.1 ± 0.2(n=24) 1.0 ± 0.1 1.1 ± 0.1 1.0 ± 0.1(n=30) 1.0 ± 0.2 1.0 ± 0.2 1.0 ± 0.2 1.0 ± 0.2(n=26) −0.002 (−0.004, −0.0004) 0.03 0.014 −0.0006 (−0.002, 0.001) 0.13 0.486
BMC (g) 61.1 ± 12.6(n=24) 57.1 ± 8.9 59.6 ± 11.0 54.5 ± 9.3(n=30) 55.9 ± 17.6 55.4 ± 11.3 54.2 ± 10.8 53.5 ± 13.5(n=26) −0.1 (−0.3, −0.02) 0.02 0.025 0.06 (−0.05, 0.17) 0.31 0.306
BA (cm2) 55.7 ± 5.2(n=24) 55.7 ± 4.0 56.4 ± 5.8 54.8 ± 5.2(n=30) 55.9 ± 7.2 54.9 ± 4.8 55.6 ± 6.8 54.6 ± 5.6(n=26) −0.02 (−0.08, 0.03) 0.003 0.405 0.09 (0.05, 0.13) 0.56 <0.0001
Total hip
aBMD (g/cm2) 1.1 ± 0.2 1.0 ± 0.1 1.1 ± 0.1 1.0 ± 0.1(n=29) 0.9 ± 0.2 1.0 ± 0.1(n=33) 0.9 ± 0.1(n=29) 0.9 ± 0.2(n=27) −0.004 (−0.006, −0.003) 0.14 <0.0001 −0.003 (−0.005, −0.002) 0.20 <0.0001
BMC (g) 35.4 ± 6.2 34.2 ± 4.2 35.8 ± 4.5 33.0 ± 4.4(n=29) 31.4 ± 5.9 31.6 ± 4.7(n=33) 31.1 ± 4.4(n=29) 29.7 ± 6.3(n=27) −0.15 (−0.2, −0.1) 0.12 <0.0001 −0.07 (−0.1, −0.02) 0.32 0.005
BA (cm2) 33.3 ± 2.1 33.5 ± 2.6 34.1 ± 2.3 33.4 ± 2.2(n=29) 33.8 ± 2.6 33.0 ± 2.1(n=33) 34.0 ± 2.0(n=29) 33. 0 ± 2.2(n=27) −0.009 (−0.03, 0.02) 0.002 0.468 0.04 (0.02, 0.06) 0.52 <0.0001
Femoral neck
aBMD (g/cm2) 1.0 ± 0.1 1.0 ± 0.1 1.0 ± 0.1 0.9 ± 0.1(n=30) 0.9 ± 0.1 0.9 ± 0.1 0.8 ± 0.1(n=29) 0.8 ± 0.2(n=27) −0.005 (−0.007, −0.004) 0.22 <0.0001 −0.004 (−0.006, −0.003) 0.31 <0.0001
BMC (g) 5.0 ± 1.0 4.7 ± 0.7 5.0 ± 0.7 4.4 ± 0.6(n=30) 4.3 ± 0.8 4.3 ± 0.7 4.0 ± 0.6(n=29) 3.8 ± 0.8(n=27) −0.03 (−0.04, −0.02) 0.20 <0.0001 −0.02 (−0.03, −0.01) 0.36 <0.0001
BA (cm2) 4.8 ± 0.6 5.0 ± 0.6 5.1 ± 0.5 4.8 ± 0.5(n=30) 5.0 ± 0.5 5.0 ± 0.5 4.8 ± 0.4(n=29) 4.8 ± 0.6(n=27) −0.003 (−0.009, 0.002) 0.01 0.264 0.002 (−0.003, 0.008) 0.13 0.382
Radius
aBMD (g/cm2) 0.7 ± 0.1 0.7 ± 0.1 0.7 ± 0.1 0.7 ± 0.1 0.7 ± 0.1 0.7 ± 0.1 0.6 ± 0.1 0.6 ± 0.1(n=27) −0.004 (−0.005, −0.003) 0.25 <0.0001 −0.003 (−0.004, −0.002) 0.34 <0.0001
BMC (g) 12.9 ± 1.6 12.2 ± 1.7 12.5 ± 1.9 12.0 ± 1.8 11.4 ± 1.8 11.3 ± 2.1 10.6 ± 1.5 10.2 ± 2.0(n=27) −0.07 (−0.09, −0.05) 0.17 <0.0001 −0.03 (−0.05, −0.02) 0.49 <0.0001
BA (cm2) 17.3 ± 1.6 17.1 ± 2.1 17.5 ± 2.1 17.4 ± 1.8 17.6 ± 2.0 17.3 ± 2.1 17.4 ± 2.0 16.8 ± 1.7(n=27) −0.005 (−0.02, 0.02) 0.001 0.649 0.03 (0.01, 0.05) 0.41 0.001

Values are mean ± SD.

Bold indicates significance.

Adjustments were made for weight and height.

β-Coefficients are calculated with age as a continuous variable.

Superscript values indicate the group numbers.

aBMD, areal bone mineral density; BMC, bone mineral content; BA, bone area.