Table 5.
Age (yr) | 40–44 (n = 25) | 45–49 (n = 34) | 50–54 (n = 29) | 55–59 (n = 31) | 60–64 (n = 27) | 65–69 (n = 35) | 70–74 (n = 30) | 75+ (n = 28) | β-Coefficient (95% CI) | R2 | Unadjusted p-value | β-Coefficient (95% CI) | R2 | Adjusted p-value |
Whole body | ||||||||||||||
aBMD (g/cm2) | 1.2 ± 0.1(n=24) | 1.2 ± 0.1 | 1.2 ± 0.1 | 1.1 ± 0.1 | 1.1 ± 0.1 | 1.1 ± 0.1 | 1.1 ± 0.1(n=29) | 1.1 ± 0.1(n=26) | −0.003 (−0.004, −0.002) | 0.13 | <0.0001 | −0.002 (−0.003, −0.0008) | 0.34 | <0.0001 |
BMC (g) | 2,804 ± 433(n=24) | 2,632 ± 358 | 2,739 ± 433 | 2,532 ± 374 | 2,442 ± 448 | 2,433 ± 366 | 2,335 ± 299(n=29) | 2,279 ± 380(n=26) | −13.3 (−17.4, −9.2) | 0.15 | <0.0001 | −3.9 (−6.6, −1.1) | 0.66 | 0.007 |
BA (cm2) | 2,355 ± 200(n=24) | 2,275 ± 212 | 2,321 ± 233 | 2,242 ± 217 | 2,210 ± 243 | 2,175 ± 215 | 2,171 ± 204(n=29) | 2,087 ± 205(n=26) | −6.2 (−8.5, −3.9) | 0.11 | <0.0001 | −0.1 (−1.2, 1.0) | 0.83 | 0.856 |
Spine | ||||||||||||||
aBMD (g/cm2) | 1.1 ± 0.2(n=24) | 1.0 ± 0.1 | 1.1 ± 0.1 | 1.0 ± 0.1(n=30) | 1.0 ± 0.2 | 1.0 ± 0.2 | 1.0 ± 0.2 | 1.0 ± 0.2(n=26) | −0.002 (−0.004, −0.0004) | 0.03 | 0.014 | −0.0006 (−0.002, 0.001) | 0.13 | 0.486 |
BMC (g) | 61.1 ± 12.6(n=24) | 57.1 ± 8.9 | 59.6 ± 11.0 | 54.5 ± 9.3(n=30) | 55.9 ± 17.6 | 55.4 ± 11.3 | 54.2 ± 10.8 | 53.5 ± 13.5(n=26) | −0.1 (−0.3, −0.02) | 0.02 | 0.025 | 0.06 (−0.05, 0.17) | 0.31 | 0.306 |
BA (cm2) | 55.7 ± 5.2(n=24) | 55.7 ± 4.0 | 56.4 ± 5.8 | 54.8 ± 5.2(n=30) | 55.9 ± 7.2 | 54.9 ± 4.8 | 55.6 ± 6.8 | 54.6 ± 5.6(n=26) | −0.02 (−0.08, 0.03) | 0.003 | 0.405 | 0.09 (0.05, 0.13) | 0.56 | <0.0001 |
Total hip | ||||||||||||||
aBMD (g/cm2) | 1.1 ± 0.2 | 1.0 ± 0.1 | 1.1 ± 0.1 | 1.0 ± 0.1(n=29) | 0.9 ± 0.2 | 1.0 ± 0.1(n=33) | 0.9 ± 0.1(n=29) | 0.9 ± 0.2(n=27) | −0.004 (−0.006, −0.003) | 0.14 | <0.0001 | −0.003 (−0.005, −0.002) | 0.20 | <0.0001 |
BMC (g) | 35.4 ± 6.2 | 34.2 ± 4.2 | 35.8 ± 4.5 | 33.0 ± 4.4(n=29) | 31.4 ± 5.9 | 31.6 ± 4.7(n=33) | 31.1 ± 4.4(n=29) | 29.7 ± 6.3(n=27) | −0.15 (−0.2, −0.1) | 0.12 | <0.0001 | −0.07 (−0.1, −0.02) | 0.32 | 0.005 |
BA (cm2) | 33.3 ± 2.1 | 33.5 ± 2.6 | 34.1 ± 2.3 | 33.4 ± 2.2(n=29) | 33.8 ± 2.6 | 33.0 ± 2.1(n=33) | 34.0 ± 2.0(n=29) | 33. 0 ± 2.2(n=27) | −0.009 (−0.03, 0.02) | 0.002 | 0.468 | 0.04 (0.02, 0.06) | 0.52 | <0.0001 |
Femoral neck | ||||||||||||||
aBMD (g/cm2) | 1.0 ± 0.1 | 1.0 ± 0.1 | 1.0 ± 0.1 | 0.9 ± 0.1(n=30) | 0.9 ± 0.1 | 0.9 ± 0.1 | 0.8 ± 0.1(n=29) | 0.8 ± 0.2(n=27) | −0.005 (−0.007, −0.004) | 0.22 | <0.0001 | −0.004 (−0.006, −0.003) | 0.31 | <0.0001 |
BMC (g) | 5.0 ± 1.0 | 4.7 ± 0.7 | 5.0 ± 0.7 | 4.4 ± 0.6(n=30) | 4.3 ± 0.8 | 4.3 ± 0.7 | 4.0 ± 0.6(n=29) | 3.8 ± 0.8(n=27) | −0.03 (−0.04, −0.02) | 0.20 | <0.0001 | −0.02 (−0.03, −0.01) | 0.36 | <0.0001 |
BA (cm2) | 4.8 ± 0.6 | 5.0 ± 0.6 | 5.1 ± 0.5 | 4.8 ± 0.5(n=30) | 5.0 ± 0.5 | 5.0 ± 0.5 | 4.8 ± 0.4(n=29) | 4.8 ± 0.6(n=27) | −0.003 (−0.009, 0.002) | 0.01 | 0.264 | 0.002 (−0.003, 0.008) | 0.13 | 0.382 |
Radius | ||||||||||||||
aBMD (g/cm2) | 0.7 ± 0.1 | 0.7 ± 0.1 | 0.7 ± 0.1 | 0.7 ± 0.1 | 0.7 ± 0.1 | 0.7 ± 0.1 | 0.6 ± 0.1 | 0.6 ± 0.1(n=27) | −0.004 (−0.005, −0.003) | 0.25 | <0.0001 | −0.003 (−0.004, −0.002) | 0.34 | <0.0001 |
BMC (g) | 12.9 ± 1.6 | 12.2 ± 1.7 | 12.5 ± 1.9 | 12.0 ± 1.8 | 11.4 ± 1.8 | 11.3 ± 2.1 | 10.6 ± 1.5 | 10.2 ± 2.0(n=27) | −0.07 (−0.09, −0.05) | 0.17 | <0.0001 | −0.03 (−0.05, −0.02) | 0.49 | <0.0001 |
BA (cm2) | 17.3 ± 1.6 | 17.1 ± 2.1 | 17.5 ± 2.1 | 17.4 ± 1.8 | 17.6 ± 2.0 | 17.3 ± 2.1 | 17.4 ± 2.0 | 16.8 ± 1.7(n=27) | −0.005 (−0.02, 0.02) | 0.001 | 0.649 | 0.03 (0.01, 0.05) | 0.41 | 0.001 |
Values are mean ± SD.
Bold indicates significance.
Adjustments were made for weight and height.
β-Coefficients are calculated with age as a continuous variable.
Superscript values indicate the group numbers.
aBMD, areal bone mineral density; BMC, bone mineral content; BA, bone area.