Table 6.
Age (yr) | 40–44 (n = 28) | 45–49 (n = 32) | 50–54 (n = 30) | 55–59 (n = 31) | 60–64 (n = 31) | 65–69 (n = 33) | 70–74 (n = 30) | 75+ (n = 34) | β-Coefficient (95% CI) | R2 | Unadjusted p-value | β-Coefficient (95% CI) | R2 | Adjusted p-value |
Whole body | ||||||||||||||
aBMD (g/cm2) | 1.1 ± 0.1(n=27) | 1.1 ± 0.1 | 1.0 ± 0.1 | 1.0 ± 0.1(n=30) | 1.0 ± 0.1 | 0.9 ± 0.1 | 0.9 ± 0.1(n=29) | 0.9 ± 0.1(n=30) | −0.005 (−0.006, −0.005) | 0.37 | <0.0001 | −0.004 (−0.005, −0.003) | 0.54 | <0.0001 |
BMC (g) | 2,273 ± 361(n=27) | 2,210 ± 366 | 2,081 ± 449 | 1,827 ± 300(n=30) | 1,752 ± 252 | 1,749 ± 369 | 1,679 ± 368(n=29) | 1,538 ± 303(n=30) | −18.9 (−22.5, −15.3) | 0.31 | <0.0001 | −10.6 (−12.9, −8.2) | 0.75 | <0.0001 |
BA (cm2) | 2,025 ± 193(n=27) | 2,041 ± 229 | 1,974 ± 250 | 1,840 ± 201(n=30) | 1,820 ± 165 | 1,839 ± 241 | 1,781 ± 231(n=29) | 1,703 ± 227(n=30) | −8.7 (−11.0, −6.5) | 0.20 | <0.0001 | −−2.8 (−4.0, −1.7) | 0.83 | <0.0001 |
Spine | ||||||||||||||
aBMD (g/cm2) | 1.1 ± 0.1(n=27) | 1.0 ± 0.1 | 0.9 ± 0.2 | 0.8 ± 0.1(n=30) | 0.8 ± 0.1 | 0.8 ± 0.2(n=32) | 0.8 ± 0.1(n=29) | 0.7 ± 0.1(n=31) | −0.008 (−0.01, −0.007) | 0.34 | <0.0001 | −0.006 (−0.008, −0.005) | 0.50 | <0.0001 |
BMC (g) | 53.3 ± 9.5(n=27) | 48.7 ± 10.1 | 45.5 ± 10.1 | 37.6 ± 8.1(n=30) | 38.2 ± 7.2 | 37.6 ± 10.2(n=32) | 35.7 ± 9.2(n=29) | 32.9 ± 8.5(n=31) | −0.5 (−0.6, −0.4) | 0.29 | <0.0001 | −0.3 (−0.4, −0.2) | 0.58 | <0.0001 |
BA (cm2) | 48.6 ± 3.6(n=27) | 48.5 ± 4.9 | 48.5 ± 4.4 | 46.4 ± 5.4(n=30) | 46.9 ± 4.3 | 47.7 ± 5.2(n=32) | 45.6 ± 5.1(n=29) | 44.9 ± 6.1(n=31) | −0.1 (−0.2, −0.1) | 0.07 | <0.0001 | −0.007 (−0.05, 0.03) | 0.47 | 0.734 |
Total hip | ||||||||||||||
aBMD (g/cm2) | 1.0 ± 0.2(n=27) | 1.0 ± 0.1(n=30) | 0.9 ± 0.1 | 0.8 ± 0.1(n=30) | 0.8 ± 0.1(n=29) | 0.7 ± 0.1(n=32) | 0.7 ± 0.1(n=29) | 0.7 ± 0.1(n=33) | −0.009 (−0.01, −0.008) | 0.44 | <0.0001 | −0.008 (−0.009, −0.006) | 0.51 | <0.0001 |
BMC (g) | 28.6 ± 5.0(n=27) | 28.1 ± 4.8(n=30) | 25.0 ± 4.5 | 23.0 ± 3.3(n=30) | 22.0 ± 3.2(n=29) | 21.9 ± 3.6(n=32) | 20.9 ± 4.4(n=29) | 19.2 ± 3.9(n=33) | −0.2 (−0.3, −0.2) | 0.35 | <0.0001 | −0.2 (−0.2, −0.1) | 0.51 | <0.0001 |
BA (cm2) | 28.3 ± 2.1(n=27) | 28.5 ± 1.9(n=30) | 28.8 ± 2.1 | 28.3 ± 2.0(n=30) | 28.5 ± 1.9(n=29) | 29.6 ± 2.3(n=32) | 28.4 ± 2.3(n=29) | 28.6 ± 2.3(n=33) | 0.004 (−0.02, 0.03) | 0.0005 | 0.719 | 0.04 (0.02, 0.06) | 0.39 | <0.0001 |
Femoral neck | ||||||||||||||
aBMD (g/cm2) | 1.0 ± 0.1(n=27) | 1.0 ± 0.1(n=30) | 0.9 ± 0.1 | 0.8 ± 0.1(n=30) | 0.8 ± 0.1(n=29) | 0.7 ± 0.1(n=32) | 0.7 ± 0.1(n=29) | 0.7 ± 0.1(n=32) | −0.008 (−0.01, −0.007) | 0.45 | <0.0001 | −0.007 (−0.008, −0.006) | 0.54 | <0.0001 |
BMC (g) | 4.1 ± 0.8(n=27) | 4.0 ± 0.8(n=30) | 3.6 ± 0.8 | 3.3 ± 0.7(n=30) | 3.2 ± 0.6(n=29) | 3.1 ± 0.7(n=32) | 3.0 ± 0.7(n=29) | 2.6 ± 0.7(n=32) | −0.04 (−0.04, −0.03) | 0.29 | <0.0001 | −0.03 (−0.03, −0.02) | 0.44 | <0.0001 |
BA (cm2) | 4.2 ± 0.7(n=27) | 4.1 ± 0.6(n=30) | 4.2 ± 0.6 | 4.1 ± 0.7(n=30) | 4.1 ± 0.6(n=29) | 4.2 ± 0.7(n=32) | 4.2 ± 0.6(n=29) | 3.9 ± 0.7(n=32) | −0.005 (−0.01, 0.002) | 0.01 | 0.124 | 0.001 (−0.006, 0.008) | 0.14 | 0.775 |
Radius | ||||||||||||||
aBMD (g/cm2) | 0.6 ± 0.1(n=27) | 0.6 ± 0.1 | 0.6 ± 0.1 | 0.5 ± 0.1(n=29) | 0.5 ± 0.1 | 0.4 ± 0.1 | 0.5 ± 0.1 | 0.4 ± 0.1(n=32) | −0.006 (−0.007, −0.005) | 0.44 | <0.0001 | −0.005 (−0.005, −0.004) | 0.58 | <0.0001 |
BMC (g) | 9.0 ± 1.5(n=27) | 8.8 ± 1.2 | 8.3 ± 1.8 | 7.0 ± 1.2(n=29) | 7.1 ± 1.3 | 6.8 ± 1.6 | 6.6 ± 1.4 | 6.1 ± 1.2(n=32) | −0.08 (−0.09, −0.06) | 0.31 | <0.0001 | −0.05 (−0.06, −0.04) | 0.60 | <0.0001 |
BA (cm2) | 14.5 ± 1.3(n=27) | 15.0 ± 1.7 | 14.7 ± 1.8 | 14.8 ± 1.5(n=29) | 15.0 ± 1.6 | 15.6 ± 1.2 | 14.7 ± 1.5 | 15.3 ± 1.9(n=32) | 0.01 (−0.003, 0.03) | 0.01 | 0.103 | 0.04 (0.03, 0.05) | 0.41 | <0.0001 |
Values are mean ± SD.
Bold indicates significance.
Adjustments were made for weight and height.
β-Coefficients are calculated with age as a continuous variable.
Superscript values indicate the group numbers.
aBMD, areal bone mineral density; BMC, bone mineral content; BA, bone area.