Table 7.
Peripheral quantitative computed tomography bone parameters in men.
| Age (yr) | 40–44 (n = 25) | 45–49 (n = 34) | 50–54 (n = 29) | 55–59 (n = 31) | 60–64 (n = 27) | 65–69 (n = 35) | 70–74 (n = 30) | 75+ (n = 28) | β-Coefficient (95% CI) | R2 | Unadjusted p-value | β-Coefficient (95% CI) | R2 | Adjusted p-value |
| Radius | ||||||||||||||
| 4% Total vBMD (mg/cm3) | 362.5 ± 45.1(n=22) | 327.3 ± 39.6(n=27) | 327.0 ± 45.0(n=25) | 331.9 ± 56.2(n=26) | 296.2 ± 52.5(n=24) | 292.6 ± 55.8(n=25) | 276.0 ± 46.2(n=25) | 292.2 ± 57.5(n=23) | −1.92 (−2.5, −1.3) | 0.18 | <0.0001 | −1.77 (−2.4, −1.2) | 0.20 | <0.0001 |
| 4% Trab.vBMD (mg/cm3) | 206.5 ± 44.7(n=22) | 181.6 ± 39.7(n=27) | 173.1 ± 31.3(n=25) | 177.3 ± 41.8(n=26) | 152.3 ± 40.2(n=24) | 147.9 ± 38.6(n=25) | 149.6 ± 34.6(n=25) | 140.2 ± 35.2(n=23) | −1.57 (−2.0, −1.1) | 0.21 | <0.0001 | −1.45 (−1.9, −1.0) | 0.23 | <0.0001 |
| 33% Ct.vBMD (mg/cm3) | 1,228.9 ± 35.8(n=24) | 1,230.8 ± 37.8(n=29) | 1,235.0 ± 33.8(n=25) | 1,224.0 ± 34.1(n=28) | 1,203.2 ± 44.9(n=23) | 1,203.8 ± 25.9(n=26) | 1,192.5 ± 30.1(n=25) | 1,207.0 ± 31.4(n=23) | −0.96 (−1.4, −0.6) | 0.10 | <0.0001 | −0.94 (−1.4, −0.5) | 0.11 | <0.0001 |
| 33% CSA (mm2) | 139.5 ± 18.0(n=24) | 135.2 ± 20.2(n=29) | 142.8 ± 20.0(n=25) | 140.9 ± 16.5(n=28) | 142.6 ± 17.4(n=23) | 134.7 ± 19.3(n=26) | 138.8 ± 20.4(n=25) | 133.4 ± 14.9(n=23) | −0.12 (−0.3, 0.1) | 0.01 | 0.274 | 0.14 (−0.1, 0.3) | 0.19 | 0.188 |
| 33% Ct.Th (mm) | 2.7 ± 0.3(n=24) | 2.7 ± 0.3(n=29) | 2.8 ± 0.3(n=25) | 2.7 ± 0.3(n=28) | 2.6 ± 0.3(n=23) | 2.6 ± 0.4(n=26) | 2.4 ± 0.4(n=25) | 2.5 ± 0.3(n=23) | −0.01 (−0.01, −0.01) | 0.11 | <0.0001 | −0.01 (−0.01, −0.003) | 0.16 | 0.001 |
| 33% SSI (mm3) | 310.1 ± 0.3(n=24) | 293.5 ± 63.0(n=29) | 354.2 ± 80.3(n=25) | 305.3 ± 69.8(n=28) | 332.6 ± 61.7(n=23) | 297.9 ± 84.6(n=26) | 309.2 ± 86.0(n=25) | 287.9 ± 51.5(n=23) | −0.60 (−1.4, 0.2) | 0.01 | 0.150 | 0.32 (−0.5, 1.1) | 0.17 | <0.0001 |
| Tibia | ||||||||||||||
| 4% Total vBMD (mg/cm3) | 316.9 ± 43.7 | 283.0 ± 38.3(n=30) | 285.2 ± 39.2(n=25) | 275.8 ± 37.1(n=28) | 255.1 ± 42.5(n=25) | 259.8 ± 48.3(n=32) | 245.5 ± 33.0(n=27) | 249.9 ± 40.1(n=24) | −1.62 (−2.1, −1.2) | 0.19 | <0.0001 | −1.45 (−1.9, −1.0) | 0.31 | <0.0001 |
| 4% Trab.vBMD (mg/cm3) | 204.4 ± 40.3(n=24) | 186.8 ± 33.9(n=30) | 181.6 ± 29.3(n=25) | 172.8 ± 26.9(n=28) | 169.5 ± 32.2(n=25) | 170.0 ± 37.0(n=32) | 161.2 ± 25.6(n=27) | 163.0 ± 30.0(n=24) | −0.96 (−1.3, −0.6) | 0.12 | <0.0001 | −0.81 (−1.2, −0.5) | 0.25 | <0.0001 |
| 38% Ct.vBMD (mg/cm3) | 1,219.8 ± 33.8 | 1,218.6 ± 29.0(n=31) | 1,220.1 ± 37.1(n=25) | 1,218.7 ± 39.6(n=28) | 1,199.5 ± 42.6(n=26) | 1,204.3 ± 31.0(n=32) | 1,193.6 ± 35.5(n=27) | 1,202.4 ± 32.1(n=24) | −0.62 (−1.0, −0.2) | 0.05 | 0.002 | −0.79 (−1.2, −0.4) | 0.08 | <0.0001 |
| 38% CSA (mm2) | 472.2 ± 61.4 | 461.5 ± 64.3(n=31) | 453.3 ± 52.2(n=25) | 455.4 ± 39.1(n=28) | 462.9 ± 66.6(n=26) | 442.3 ± 55.1(n=32) | 452.5 ± 63.4(n=27) | 425.4 ± 38.8(n=24) | −0.87 (−1.5, −0.3) | 0.04 | 0.005 | 0.004 (−0.6, 0.6) | 0.28 | 0.989 |
| 38% Ct.Th (mm) | 5.0 ± 0.5 | 5.0 ± 0.5(n=31) | 5.0 ± 0.4(n=25) | 4.9 ± 0.5(n=28) | 4.6 ± 0.6(n=26) | 4.7 ± 0.6(n=32) | 4.8 ± 0.7(n=27) | 4.8 ± 0.6(n=24) | −0.01 (−0.01, −0.001) | 0.02 | 0.026 | −0.004 (−0.01, 0.002) | 0.07 | 0.203 |
| 38% SSI (mm3) | 2,129.2 ± 360.9 | 2,043.5 ± 364.8(n=31) | 2,033.3 ± 320.1(n=25) | 2,046.3 ± 253.2(n=28) | 1,928.8 ± 379.0(n=26) | 1,896.7 ± 314.8(n=32) | 1,949.7 ± 354.9(n=27) | 1,839.5 ± 212.5(n=24) | −6.37 (−9.9, −2.9) | 0.06 | <0.0001 | −1.54 (−4.9, 1.8) | 0.27 | 0.362 |
Values are mean ± SD. Bold indicates significance. Adjustments were made for weight and height. β-Coefficients are calculated with age as a continuous variable. Superscript values indicate the group numbers. vBMD, volumetric bone mineral density; Trab, trabecular; Ct, cortical; Th, thickness; CSA, cross-sectional area; SSI, stress strain index.