Table 1.

White blood cell (WBC) count and arterial stiffness.

Study population	Findings	Reference
69 consecutive familial Mediterranean fever (FMF) patients and 35 controls	Pulse wave velocity (PWV) was correlated to serum C-reactive protein (CRP), WBC, erythrocyte sedimentation rate, fibrinogen, and neutrophil/lymphocyte ratio	Cakar et al. (58)
29 patients with hematologic malignancies (8 with multiple myeloma, 2 with Hodgkin’s lymphoma, 11 with non-Hodgkin’s lymphoma, 6 with myelodysplastic syndrome, and 2 with chronic myeloid leukemia)	An inverse correlation was found between PWV and neutrophil count (r = -0.45). Multiple regression analysis found significant associations between augmentation index (AI) and PWV, and WBC and platelet count, respectively	Mozos and Mihaescu (52)
20 patients with solid tumors (colon, lung, renal, laryngeal, pancreas, mammary and testicular cancer, and malignant melanoma) and 26 healthy controls	Significant higher values were obtained for PWV, AI and central hemodynamic variables in cancer patients compared to healthy controls. The best correlation was found between AI and neutrophil count and WBC, respectively. PWV as a measure of arterial stiffness was significantly associated with neutrophilia, monocytosis, and lymphopenia. AI was significantly associated with neutrophilia	Mozos and Mihaescu (53)
500 subjects included in the MARK study, aged 35–74 years	Monocyte count was positively correlated with central augmentation index (CAIx) in women, also after adjusting for age and other confounders	Gomez-Sanchez et al. (56)
886 postmenopausal women with hypertension	A direct relationship between neutrophil count and 24-h ambulatory pulse pressure (PP) was observed. Increased arterial stiffness, as reflected in high values of 24-h ambulatory PP, is an adverse prognostic marker in postmenopausal women with hypertension and can be used as an additional correlate for systemic inflammation	Angeli et al. (50)
23 colchicine-treated patients with FMF and 23 age- and sex-matched controls	PWV was slightly higher in colchicine-treated FMF patients than in control subjects (P = 0.05) and significantly correlated with age and leukocyte count, but no correlations between PWV and CRP levels or blood pressure could be observed PWV was furthermore found to be generally influenced by age and body mass index	Yildiz et al. (57)