Table 2.
Neutrophil/lymphocyte ratio (NLR) and arterial stiffness.
Study population | Findings | Reference |
---|---|---|
103 patients with STEMI who underwent successful primary percutaneous coronary intervention | Aortic velocity propagation (AVP) values improved after successful treatment in STEMI patients. The increment in AVP values was closely correlated with a decrement in NLR | Yaman et al. (69) |
145 consecutive patients admitted with stable angina pectoris or acute coronary syndrome (ACS) | Augmentation index and pulse wave velocity (PWV) were positively associated with NLR. NLR might be used to risk-stratify patients, considering arterial stiffness in patients with coronary heart disease, especially in the presence of ACS | Tanindi et al. (44) |
76 persons with type 1 diabetes and 36 healthy controls | The observed significant negative correlation between the NLR and markers of aortic stiffness in patients with type 1 diabetes suggests a strong association between inflammation and arterial stiffness | Ayhan et al. (19) |
402 participants:133 control subjects, 138 diabetic subjects without diabetic retinopathy (DR) and 131 patients with DR | NLR and PWV were elevated both in type 2 diabetic and in DR. NLR could be independently associated with PWV | Wang et al. (67) |
512 postmenopausal women with a similar socioeconomic background (204 patients with osteoporosis, 208 controls) | NLR and PWV were elevated in osteoporosis. Statistical analysis of collected data revealed a significant correlation between NLR and PWV after adjusting for confounders in osteoporosis patients, but not in the control group | Yu et al. (66) |
52 autosomal dominant polycystic kidney disease patients and 25 controls | Pentraxin 3 and C-reactive protein were not correlated with arterial elasticity, while NLR was significantly negatively correlated with large artery elasticity index | Gul et al. (75) |
849 Korean adults in a health examination program | A higher NLR was independently associated with arterial stiffness and coronary calcium score | Park et al. (73) |