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. 2017 Aug 31;8:1058. doi: 10.3389/fimmu.2017.01058

Table 2.

Neutrophil/lymphocyte ratio (NLR) and arterial stiffness.

Study population Findings Reference
103 patients with STEMI who underwent successful primary percutaneous coronary intervention Aortic velocity propagation (AVP) values improved after successful treatment in STEMI patients. The increment in AVP values was closely correlated with a decrement in NLR Yaman et al. (69)
145 consecutive patients admitted with stable angina pectoris or acute coronary syndrome (ACS) Augmentation index and pulse wave velocity (PWV) were positively associated with NLR. NLR might be used to risk-stratify patients, considering arterial stiffness in patients with coronary heart disease, especially in the presence of ACS Tanindi et al. (44)
76 persons with type 1 diabetes and 36 healthy controls The observed significant negative correlation between the NLR and markers of aortic stiffness in patients with type 1 diabetes suggests a strong association between inflammation and arterial stiffness Ayhan et al. (19)
402 participants:133 control subjects, 138 diabetic subjects without diabetic retinopathy (DR) and 131 patients with DR NLR and PWV were elevated both in type 2 diabetic and in DR. NLR could be independently associated with PWV Wang et al. (67)
512 postmenopausal women with a similar socioeconomic background (204 patients with osteoporosis, 208 controls) NLR and PWV were elevated in osteoporosis. Statistical analysis of collected data revealed a significant correlation between NLR and PWV after adjusting for confounders in osteoporosis patients, but not in the control group Yu et al. (66)
52 autosomal dominant polycystic kidney disease patients and 25 controls Pentraxin 3 and C-reactive protein were not correlated with arterial elasticity, while NLR was significantly negatively correlated with large artery elasticity index Gul et al. (75)
849 Korean adults in a health examination program A higher NLR was independently associated with arterial stiffness and coronary calcium score Park et al. (73)