Skip to main content
. 2017 Sep 4;7:10313. doi: 10.1038/s41598-017-10875-0

Figure 9.

Figure 9

Tetracyclines protect C. elegans from the toxicity induced by p17. (a,b,d) N2 nematodes (100 worms/100 µL) were incubated for 2 h with 4 nM p17 or myr-p17 in the absence or presence of: 200 µM Congo red, 50 µM tetracyclines, 5 mM N-acetylcysteine (NAC), 25 µM clioquinol (CQ), or 50 µM gentamicin, in the absence of OP50 E. coli. Control worms were fed 10 mM PB (pH 7.4) (vehicle). Mean ± SE (N = 20 worms/group). **P < 0.01 vs. vehicle and °°P < 0.01 vs. p17 alone, one-way ANOVA and Bonferroni post hoc test. (c) Dose-response effect of tetracycline. Control worms received vehicle alone (dotted line). Mean ± SE (n = 20 worms/group).