Table 1.
Susceptibility of intracellular amastigotes of Leishmania isolates to Miltefosine (MIL), represented by EC50 values.
| Serial No. | Isolates | MIL EC50 ± SD (µM) |
|---|---|---|
| 1 | AG83 | 4.39 ± 0.43 |
| 2 | T2 | 4.69 ± 0.28 |
| 3 | T3 | 2.39 ± 0.025 |
| 4 | T4 | 3.73 ± 1.34 |
| 5 | T7 | 2.47 ± 0.13 |
| 6 | M1 | 3.88 ± 0.33 |
| 7 | PG2 | 3.99 ± 0.59 |
| 8 | PG3 | 2.28 ± 0.11 |
| 9 | PG4 | 3.78 ± 0.47 |
| 10 | RAJ-04 | 2.44 ± 0.58 |
| 11 | RAJ-05 | 2.70 ± 0.58 |
| 12 | RAJ-07 | 3.09 ± 0.27 |
| 13 | P1 | 4.24 ± 0.15 |
| 14 | BI | 3.91 ± 0.89 |
| 15 | BHU581 | 2.14 ± 0.33 |
| 16 | BHU569 | 2.09 ± 0.48 |
| 17 | BHU568 | 2.08 ± 0.41 |
| 18 | BHU572 | 1.89 ± 0.26 |
| 19 | BHU573 | 3.19 ± 0.48 |
| 20 | BHU574 | 1.74 ± 0.10 |
| 21 | BHU575 | 2.75 ± 0.41 |
| 22 | BHU592 | 2.80 ± 0.24 |
| 23 | BHU860 | 4.66 ± 0.82 |
| 24 | BHU965 | 5.35 ± 0.83 |
| 25 | T8 | 4.29 ± 0.59 |
| 26 | P2 | 3.66 ± 0.47 |
| 27 | T9 | 13.47 ± 0.87 |
Serial number in bold and regular denoted unresponsive (MIL-R) and sensitive (MIL-S) to MIL, respectively. All the isolates were MIL-S except serial no. 27, denoting MIL-R isolate (T9). Results were given as mean ± SD.