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. 2017 Sep 4;7:10330. doi: 10.1038/s41598-017-09720-1

Table 1.

Susceptibility of intracellular amastigotes of Leishmania isolates to Miltefosine (MIL), represented by EC50 values.

Serial No. Isolates MIL EC50 ± SD (µM)
1 AG83 4.39 ± 0.43
2 T2 4.69 ± 0.28
3 T3 2.39 ± 0.025
4 T4 3.73 ± 1.34
5 T7 2.47 ± 0.13
6 M1 3.88 ± 0.33
7 PG2 3.99 ± 0.59
8 PG3 2.28 ± 0.11
9 PG4 3.78 ± 0.47
10 RAJ-04 2.44 ± 0.58
11 RAJ-05 2.70 ± 0.58
12 RAJ-07 3.09 ± 0.27
13 P1 4.24 ± 0.15
14 BI 3.91 ± 0.89
15 BHU581 2.14 ± 0.33
16 BHU569 2.09 ± 0.48
17 BHU568 2.08 ± 0.41
18 BHU572 1.89 ± 0.26
19 BHU573 3.19 ± 0.48
20 BHU574 1.74 ± 0.10
21 BHU575 2.75 ± 0.41
22 BHU592 2.80 ± 0.24
23 BHU860 4.66 ± 0.82
24 BHU965 5.35 ± 0.83
25 T8 4.29 ± 0.59
26 P2 3.66 ± 0.47
27 T9 13.47 ± 0.87

Serial number in bold and regular denoted unresponsive (MIL-R) and sensitive (MIL-S) to MIL, respectively. All the isolates were MIL-S except serial no. 27, denoting MIL-R isolate (T9). Results were given as mean ± SD.