Table 1.
Summary of gene annotation for the flanking genes on the ancestral locus of HSP47/SERPINH1 on the scaffold00131 from Japanese lamprey (L. japonicum) genome, A total 45 genes are residing on this locus of size 1 Mb. The gene g32.t1 is LjaHSP47/SERPINH1 and the g19.t1 is P2RY6-like GPCR (also known as lysophosphatic acid receptor, LPA6R) and these two genes are conserved in several vertebrate genomes (Fig. 3) and hence marked in red color. Gene annotation was performed using BLAST2GO 3.0 8.
| Gene ID | Gene Annotation# | Protein Length | e-Value | Mean Similarity |
|---|---|---|---|---|
| g1.t1 | diacylglycerol kinase partial | 99 | 5,40E − 57 | 96% |
| g2.t1 | —NA—$ | 109 | — | — |
| g3.t1 | —NA— | 108 | — | — |
| g4.t1 | phosphatidylinositol-glycan biosynthesis class f protein | 207 | 2,10E − 33 | 76,05% |
| g5.t1 | ovotransferrin-like | 794 | 0,00E + 00 | 58,80% |
| g6.t1 | conserved oligomeric golgi complex subunit 3 | 913 | 0,00E + 00 | 74,25% |
| g7.t1 | hypothetical chloroplast rf2 | 813 | 2,70E − 18 | 50,30% |
| g8.t1 | glypican- partial | 202 | 3,80E − 07 | 68,55% |
| g9.t1 | glypican-5 isoform × 25 | 537 | 1,40E − 101 | 60,35% |
| g10.t1 | endoplasmic reticulum-golgi intermediate compartment protein partial | 161 | 1,20E − 86 | 88,15% |
| g11.t1 | endoplasmic reticulum-golgi intermediate compartment protein 3 isoform × 1 | 266 | 2,50E − 89 | 76,95% |
| g12.t1 | progestin and adipoq receptor family member 9 | 354 | 4,10E − 74 | 59,30% |
| g13.t1 | procollagen c-endopeptidase enhancer 2 | 389 | 3,10E − 64 | 52,75% |
| g14.t1 | short transient receptor potential channel 1 | 497 | 0,00E + 00 | 84,20% |
| g15.t1 | inhibitor of nuclear factor kappa-b kinase-interacting protein isoform × 1 | 254 | 5,30E − 04 | 47,44% |
| g16.t1 | ninein-like protein | 366 | 4,70E − 12 | 48,70% |
| g17.t1 | nucleoredoxin-like protein 2 | 128 | 2,00E − 15 | 55,45% |
| g18.t1 | —NA— | 169 | — | — |
| g19.t1 | lysophosphatidic acid receptor 6, P2RY6-like GPCR* | 404 | 2,60E − 54 | 57,85% |
| g20.t1 | ef-hand calcium-binding domain-containing protein 2 | 82 | 5,50E − 26 | 85,10% |
| g21.t1 | —NA— | 70 | — | — |
| g22.t1 | coiled-coil domain-containing protein 160 | 326 | 7,20E − 17 | 47,40% |
| g23.t1 | low quality protein: wd repeat-containing protein 78 | 665 | 0,00E + 00 | 59,65% |
| g24.t1 | growth hormone secretagogue receptor type 1 | 260 | 4,60E − 54 | 67,65% |
| g25.t1 | fibronectin type iii domain-containing protein 3b | 843 | 2,00E − 152 | 50,75% |
| g26.t1 | —NA— | 438 | — | — |
| g27.t1 | fibronectin type iii domain-containing protein 3b | 94 | 4,80E − 08 | 70,71% |
| g28.t1 | —NA— | 201 | — | — |
| g29.t1 | —NA— | 423 | — | — |
| g30.t1 | glycerol kinase 5 | 532 | 9,10E − 175 | 64,60% |
| g31.t1 | zinc finger b-box domain-containing protein 1 | 236 | 1,70E − 14 | 42,65% |
| g32.t1 | HSP47/SERPINH1* | 470 | 1,60E − 105 | 68,05% |
| g33.t1 | lysosome-associated membrane glycoprotein 1 | 380 | 3,30E − 32 | 40,05% |
| g34.t1 | haus augmin-like complex subunit partial | 355 | 8,10E − 08 | 63,10% |
| g35.t1 | —NA— | 225 | — | — |
| g36.t1 | adp-ribosylation factor | 208 | 3,10E − 53 | 67,15% |
| g37.t1 | rcc1 and btb domain-containing protein 1 | 531 | 0,00E + 00 | 83,15% |
| g38.t1 | neuroligin-3 isoform × 4 | 656 | 0,00E + 00 | 66,25% |
| g39.t1 | neuroligin- x-linked-like | 187 | 2,50E − 69 | 70,55% |
| g40.t1 | neuroligin-2-like isoform × 5 | 164 | 2,50E − 57 | 84,95% |
| g41.t1 | —NA— | 96 | — | — |
| g42.t1 | protein ect2 isoform × 1 | 368 | 1,40E − 35 | 55,80% |
| g43.t1 | hypothetical protein H310_04227 | 72 | 7,30E − 04 | 61% |
| g44.t1 | protein ect2 isoform × 1 | 1002 | 5,30E − 101 | 73,35% |
| g45.t1 | gpalpp motifs-containing protein 1 | 320 | 7,90E − 56 | 55,25% |