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. 2017 Sep 4;7:10352. doi: 10.1038/s41598-017-09678-0

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Representative ultrasound B-mode images with QUS parametric overlays (described in Fig. 1) acquired from a non-responding patient prior to and at different times after the start of chemotherapy. The color bar represents a scale encompassing 35 dBr for MBF, 10 dBr/MHz for slope, 65 dBr for intercept, 3 mm for SAS, 150 µm for ASD, and 55 dB/cm³ for AAC. The scale bar represents 5 mm.