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. 2017 Sep 4;7:10316. doi: 10.1038/s41598-017-10679-2

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Confirmation of lesional area. (a) A Nissl-stained coronal section showing both the lesional and perilesional areas in the VPL. The lesional area was defined by a dense concentration of small cells (5–10 μm in diameter), which presumably includes both glial cells and blood cells. The boundary between the lesional and perilesional areas is indicated by the white dotted line (left, lesional area; right, perilesional area). Large cells (20–40 μm in diameter, arrowheads) presumed to be neurons were observed in the perilesional area. Scale bar: 50 μm. (b–f) Serial Nissl-stained coronal sections of Macaque I, spaced by approximately 600 μm, are arranged from rostral (b) to caudal (f). Note that the lesion was located within the VPL. Scale bar: mm. CM, central medial nucleus; LP, lateral posterior nucleus; MD, dorsomedial nucleus; Pul, pulvinar nucleus; SG, suprageniculate nucleus; VLc, caudal part of the ventrolateral nucleus; VPM, ventral posteromedial nucleus; VPL, ventral posterolateral nucleus; VPI, ventral posteroinferior nucleus.