Fig. 1. Forest plot of estimated odds ratio (OR) (95% confidence intervals) for aggregate or disaggregate cardiovascular disease (CVD) events as derived from available meta-analyses of randomized controlled trials on the effect of testosterone therapy (TTh) vs. placebo. MACE: major adverse cardiovascular events, AMI: acute myocardial infarction, NR: not reported, MH-OR: Mantel-Haenszed odds ratio, LL: lower limits, UL: upper limits.