Table 1. Demographic and clinical baseline characteristics of the patients.
| Characteristic | α-Lipoic acid | Placebo | P value |
|---|---|---|---|
| No. of patients | 46 | 45 | - |
| Sex, male/female | 27/19 | 20/25 | - |
| Age, yr | 64.37±7.80 | 62.40±9.10 | 0.270 |
| BMI, kg/m2 | 25.38±3.29 | 25.64±2.86 | 0.723 |
| Duration of diabetes, yr | 13.84±9.11 | 11.37±8.82 | 0.240 |
| HbA1c, % | 7.54±1.12 | 7.35±1.04 | 0.393 |
| SBP, mm Hg | 124.26±12.45 | 125.76±13.89 | 0.590 |
| DBP, mm Hg | 73.24±8.57 | 75.09±8.52 | 0.305 |
| Mean HR, beat/min | 72.54±7.91 | 70.60±7.35 | 0.228 |
| Lipid profile, mg/dL | |||
| Total cholesterol | 162.33±36.69 | 163.42±42.65 | 0.896 |
| Triglyceride | 145.67±100.67 | 133.56±79.97 | 0.527 |
| HDL-C | 48.09±12.52 | 45.51±11.03 | 0.301 |
| LDL-C | 84.03±35.22 | 87.01±31.99 | 0.705 |
| No. of patients on the medication | |||
| Oral anti-hypertensives | 33 | 26 | - |
| Statin | 27 | 26 | - |
| Insulin | 13 | 10 | - |
| Oral anti-diabetes | 31 | 24 | - |
Values are presented as mean±standard deviation.
BMI, body mass index; HbA1c, glycosylated hemoglobin; SBP, systolic blood pressure; DBP, diastolic blood pressure; HR, heart rate; HDL-C, high density lipoprotein cholesterol; LDL-C, low density lipoprotein cholesterol.