Table 1.
Characteristics and outcome measures of included studies.
| Included research (year) | E/C | Intervening measure (E/C) | Dosage of XNJ | Duration | Outcome measures |
|---|---|---|---|---|---|
| Wu et al., 1999 | 20/20 | XNJ+ CT vs. CT | 40 mL/day | 15 days | Overall response rate |
| Chen, 2006 | 39/30 | XNJ+ CT vs. CT | 20 mL/day | 20 days | Overall response rate, Hemorheology, Blood lipid |
| Zhang et al., 2006 | 32/28 | XNJ+ CT vs. CT | 30 mL/day | 15 days | Neurological deficit score |
| Li et al., 2008 | 27/27 | XNJ+ CT vs. CT | 20 mL/day | 2 weeks | GCS |
| Su, 2008 | 39/30 | XNJ+ CT vs. CT | 20 mL/day | 20 days | Overall response rate |
| Wu, 2008 | 40/40 | XNJ+ CT vs. CT | 20 mL/day | 2 weeks | Overall response rate |
| Chen and Wang, 2009 | 73/84 | XNJ+ CT vs. CT | 30 mL/day | 2 weeks | Neurological deficit score |
| Lu and Zhang, 2009 | 76/64 | XNJ+ CT vs. CT | 40 mL/day | 15 days | Neurological deficit score |
| Qiu, 2009 | 30/30 | XNJ+ CT vs. CT | 20 mL/day | 3 weeks | Hemorheology, Overall response rate, Blood lipid |
| Wu, 2009 | 54/52 | XNJ+ CT vs. CT | 20 mL/day | 2 weeks | Overall response rate, neurological deficit score |
| Jiang, 2010 | 30/28 | XNJ+ CT vs. CT | 20 mL/day | 15 days | Overall response rate |
| Lian and Dong, 2010 | 50/50 | XNJ+ CT vs. CT | 30 mL/day | 2 weeks | Overall response rate, neurological deficit score |
| Chen, 2011 | 30/30 | XNJ+ CT vs. CT | 20 mL/day | 2 weeks | Overall response rate, neurological deficit score |
| Han et al., 2011 | 43/43 | XNJ+ CT vs. CT | 20 mL/day | 20–28 days | Neurological deficit score, Overall response rate |
| Li and Hou, 2011 | 30/30 | XNJ+ CT vs. CT | 20 mL/day | 2 weeks | Neurological deficit score, Overall response rate |
| Qin et al., 2011 | 40/40 | XNJ+ CT vs. CT | 20–30 mL/day | 2 weeks | Overall response rate, neurological deficit score |
| Tong and Zhu, 2011 | 70/66 | XNJ+ CT vs. CT | 30 mL/day | 2 weeks | Overall response rate, neurological deficit score |
| Wang, 2011 | 30/30 | XNJ+ CT vs. CT | 20 mL/day | 3 weeks | Hemorheology, Blood lipid, neurological deficit score |
| Wang, 2011 | 40/40 | XNJ+ CT vs. CT | 20 mL/day | 2 weeks | Overall response rate, neurological deficit score |
| Yang, 2011 | 62/62 | XNJ+ CT vs. CT | 20 mL/day | 15 days | Overall response rate |
| Zang et al., 2011 | 49/49 | XNJ+ CT vs. CT | 20 mL/day | 2 weeks | Overall response rate |
| Li et al., 2012 | 43/43 | XNJ+ CT vs. CT | 20 mL/day | 2 weeks | Neurological deficit score, Overall response rate |
| Li et al., 2012 | 30/31 | XNJ+ CT vs. CT | 20 mL/day | 2 weeks | Neurological deficit score, Overall response rate, Blood lipid |
| Tong and Zhu, 2012 | 64/66 | XNJ+ CT vs. CT | 30 mL/day | 2 weeks | Overall response rate, neurological deficit score |
| Wang, 2012 | 100/100 | XNJ+ CT vs. CT | 20 mL/day | 30 days | NIHSS, Overall response rate |
| Dong and Fu, 2013 | 35/33 | XNJ+ CT vs. CT | 20 mL/day | 2 weeks | Neurological deficit score |
| Lou, 2013 | 75/75 | XNJ+ CT vs. CT | 40 mL/day | 2 weeks | Overall response rate, neurological deficit score |
| Qian and Jia, 2013 | 40/40 | XNJ+ CT vs. CT | 20 mL/day | 2 weeks | Overall response rate, neurological deficit score |
| Zeng, 2013 | 49/49 | XNJ+ CT vs. CT | 20 mL/day | 2 weeks | Overall response rate |
| Jia et al., 2014 | 96/96 | XNJ+ CT vs. CT | 20 mL/day | 2 weeks | Infarction size, neurological deficit score |
| Luo, 2014 | 60/60 | XNJ+ CT vs. CT | 20 mL/day | 2 weeks | Neurological deficit score, Overall response rate, ADL, Hemorheology |
| Lv, 2014 | 62/62 | XNJ+ CT vs. CT | 20 mL/day | 15 days | Overall response rate, MMPs |
| Shen et al., 2014 | 45/41 | XNJ+ CT vs. CT | 20 mL/day | 2 weeks | Overall response rate, GCS |
| Sun, 2014 | 38/38 | XNJ+ CT vs. CT | 20 mL/day | 2 weeks | Overall response rate, MMPs |
| Wang et al., 2014 | 30/30 | XNJ+ CT vs. CT | 20–30 mL/day | 2 weeks | Overall response rate, neurological deficit score |
| Wei and Shi, 2014 | 50/50 | XNJ+ CT vs. CT | 40 mL/day | 1 week | NHISS |
| Yin et al., 2014 | 52/52 | XNJ+ CT vs. CT | 20 mL/day | 2 weeks | Overall response rate, MMP-9 |
| Yin and Wei, 2014 | 20/20 | XNJ+ CT vs. CT | 20 mL/day | 2 weeks | Overall response rate, NHISS |
| Zhang, 2014 | 49/49 | XNJ+ CT vs. CT | 10 mL/day | 30 days | Neurological deficit score |
| An et al., 2015 | 64/64 | XNJ+ CT vs. CT | 20 mL/day | 2 weeks | Overall response rate, Infarction size, neurological deficit score |
| Liao et al., 2015 | 24/23 | XNJ+ CT vs. CT | 20 mL/day | NR | Overall response rate |
| Luo et al., 2015 | 50/50 | XNJ+ CT vs. CT | 10–20 mL/day | 4 weeks | Overall response rate, Hemodynamics |
| Sun et al., 2015 | 42/42 | XNJ+ CT vs. CT | 20 mL/day | NR | MMP-9, Overall response rate |
| Wang and Huang, 2015 | 60/60 | XNJ+ CT vs. CT | 10–20 mL/day | 20 days | Neurological deficit score, ADR |
| Zhao et al., 2015 | 35/35 | XNJ+ CT vs. CT | 20 mL/day | 2 weeks | Overall response rate, neurological deficit score |
| Cai and Zhao, 2016 | 58/58 | XNJ+ CT vs. CT | 20 mL/d | 2 weeks | MMPs, Overall response rate |
| Lin, 2016 | 30/30 | XNJ+ CT vs. CT | 20 mL/day | 10 days | Neurological deficit score |
| Lu et al., 2016 | 35/35 | XNJ+ CT vs. CT | 30 mL/day | 2 weeks | Overall response rate, neurological deficit score, Infarction size |
| Lu et al., 2016 | 35/35 | XNJ+ CT vs. CT | 30 mL/day | 2 weeks | ADL |
| Wang and Wang, 2016 | 72/72 | XNJ+ CT vs. CT | 20 mL/day | 30 days | Hemodynamics, Overall response rate |
| Wang and Wang, 2016 | 40/40 | XNJ+ CT vs. CT | 20 mL/day | 2 weeks | Overall response rate |
| Xiong et al., 2016 | 48/48 | XNJ+ CT vs. CT | 20 mL/day | 2 weeks | Overall response rate |
| Yang, 2016 | 40/40 | XNJ+ CT vs. CT | 20 mL/day | 15 days | Overall response rate |
E, experimental group; C, control group; NR, no report.