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. 2017 Aug 23;6(8):e73. doi: 10.1038/emi.2017.61

Table 1. Clinical manifestations of TB/cryptococcosis co-infection with regard to HIV infection.

Presenting symptoms Total Patients without HIV Patients with HIV P-value
Constitutional
 Fever 83/110a (41/54)b 59/80 (30/40) 24/30 (11/14) 0.50 (1.00)
 Nausea 16/87 (6/31) 10/68 (4/28) 6/19 (2/3) 0.18 (0.12)
 Vomiting 34/87 (13/31) 23/68 (11/28) 11/19 (2/3) 0.06 (0.77)
 Weakness 30/87 (7/31) 15/68 (5/28) 15/19 (2/3) 0.00 (0.23)
 Weight loss 14/110 (12/54) 5/80 (4/40) 9/19 (8/14) 0.00 (0.00)
 Night sweats 14/110 (5/54) 7/80 (2/40) 7/30 (3/14) 0.10 (0.20)
 Anorexia 10/110 (8/54) 6/80 (4/40) 4/30 (4/14) 0.57 (0.21)
 
Respiratory
 Cough 42/87 (5/31) 26/68 (3/28) 16/19 (2/3) 0 (0.09)
 Sputum 37/87 (4/31) 22/68 (3/28) 15/19 (1/3) 0 (0.84)
 Dyspnea 2/87 (1/31) 1/68 (0/28) 1/19 (1/3) 0.91 (0.17)
 Chest pain 18/87 (1/31) 10/68 (1/28) 8/19 (0/3) 0.02 (1.00)
 
Neurological
 Headache 44/87 (22/31) 35/68 (19/28) 9/19 (3/3) 0.75 (0.62)
 Signs of meningeal irritation 34/87 (15/31) 27/68 (14/28) 7/19 (1/3) 0.82 (1.00)
 Conscious disturbance 14/87 (7/31) 11/68 (6/28) 3/19 (1/3) 1 (1.00)
 Dizziness 3/87 (0/31) 1/68 (0/28) 2/19 (0/3) 0.23 (NDc)
 Deep reflexes 4/87 (2/31) 3/68 (1/28) 1/19 (1/3) 1.00 (0.45)
 Hearing loss 2/87 (2/31) 2/68 (2/28) 0/19 (0/3) 1.00 (1.00)
 Vision disorders 4/87 (1/31) 4/68 (1/28) 0/19 (0/3) 0.64 (1.00)
 Papilledema 10/87 (3/31) 4/68 (3/28) 6/19 (0/3) 0.01 (1.00)
 Pupil reacted sluggishly to light 3/87 (0/31) 3/68 (0/28) 0/19 (0/3) 0.83 (ND)

Abbreviations: not determined, ND; tuberculosis, TB.

a

Positive/total number of all cases.

b

Positive/total number of cases etiologically diagnosed.

c

No data.