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. 2016 Sep 20;101(6):796–800. doi: 10.1136/bjophthalmol-2016-309023

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Per cent change from baseline in diurnal intraocular pressure (IOP) at day 29 (08:00, 10:00. 12:00, 16:00 and 20:00 hours) for ONO-9054 and Xalatan. The odds of a mean IOP reduction of ≤−25%, ≤−30% and ≤−35% for ONO-9054 were 2.39, 2.37 and 4.85 times more, respectively, than the odds for Xalatan (p<0.05, post hoc analyses). The odds of an IOP reduction of ≤−30% and ≤−40% for ONO-9054 subjects were 1.9 and 2.4 times more, respectively, than the odds for Xalatan across all time points from days 8, 15 and 29 combined (*p<0.001, post hoc analyses).