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. 2017 Jan 25;9(8):e32. doi: 10.1136/neurintsurg-2016-012806.rep

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Temperature versus time from estimated arrest. The extracorporeal membrane oxygenation (ECMO) circuit flow started 52 min from arrest, systemic hypothermia via the ECMO circuit started at 3.7 hours, and cerebral selective deep hypothermia (CSDH) circuit cooling started at 13.7 hours and reached the target band for ipsilateral nasal temperature (right) (27±2°C) at 17.7 hours. The CSDH temperature was held for 12 hours until hour 29.7 and then gradual rewarming was implemented for ∼24 hours. Following the rewarming period, the CSDH circuit was shut down and removed, although the ECMO operation continued to support flow until ECMO weaning on day 3. The patient received 11 hours of cerebral temperature below 30°C (based on right nasal temperature), and over the period from initial achievement of the target temperature to the start of rewarming, the difference between the right nasal temperature and the core temperature was 5.6±0.9°C.