Table I. Patient demographics.

	Patients with BM	Patients without BM	P value *
Total patient number	123	237
Stage at initial diagnosis#			1.00, global
I	42 (34.71%)	80 (33.76%)	0.91
IA	17 (14.05%)	34 (14.35%)	1.00
IB	25 (20.66%)	46 (19.41%)	0.78
II	25 (20.66%)	49 (20.68%)	1.00
IIA	8 (6.61%)	17 (7.17%)	1.00
IIB	11 (9.09%)	22 (9.28%)	1.00
IIC	6 (4.96%)	10 (4.22%)	0.79
III	36 (29.75%)	70 (29.54%)	1.00
IIIA	11 (9.09%)	24 (10.13%)	1.00
IIIB	17 (14.05%)	30 (12.66%)	0.74
IIIC	8 (6.61%)	16 (6.75%)	1.00
IV	18 (14.88%)	38 (16.03%)	0.88
Sex
Male	88 (71.54%)	137 (57.81%)	0.12
Female	35 (28.46%)	100 (42.19%)	0.12
M:F ratio	2.51	1.37
Age at initial diagnosis	median 51, range 11-86	median 53, range 7-79	0.043, global
<40	28 (22.76%)	73 (30.80%)	0.14
40-49	28 (22.76%)	33 (13.92%)	0.038
50-59	32 (26.02%)	47 (19.83%)	0.18
>60	35 (28.46%)	84 (35.44%)	0.20
Family history of melanoma+
Yes	13 (12.50%)	35 (20.11%)	0.14
No	91 (87.50%)	139 (79.89%)	0.14

BM, brain metastasis.

^*Fisher's Exact test

^#Stage unknown in 2 patients with BM.

⁺Patient reported. Unknown for 19 patients with BM and 63 patients without BM.