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. 2017 Sep 5;14:180. doi: 10.1186/s12974-017-0951-1

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© The Author(s). 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — LPS exposure in utero generated long-term changes in glial appearance in the hippocampus on 45 DPN. a Micrograph showing increased microgliosis (red) in the hippocampus of LPS-exposed mouse. Insets on the right show enlarged image of CA1 and CA3 area. b Scatterplot of microglia cell number in the hippocampus from PBS (n = 5)- and LPS (n = 6)-exposed mice. Asterisks indicate p < 0.05. c Scatterplot of Iba-1 expression area in the hippocampus from PBS (n = 5)- and LPS (n = 6-exposed mice. Asterisks indicate p < 0.01