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. 2017 Sep 5;14:180. doi: 10.1186/s12974-017-0951-1

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© The Author(s). 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 3 — LPS exposure in utero causes reduced PPR. a, b Representative fEPSPs evoked by paired stimulation separated by 50 ms (top trace) from hippocampal slices obtained from adult control mice (a) and mice exposed to LPS in utero (d). Each trace is the average of 10 consecutively recorded voltage traces. b, e Overlay of the first (black) and second (dash line) fEPSPs. Gray bars highlight the regions where fEPSP initial slopes were measured. c Scatterplot of PPR determined by measuring the slope of the average of 10 individual trials. Asterisks indicate p < 0.001