Table 3.

Metastasis-associated genes with significant upregulation after Acu stress (but not Rep), returning to normal after recovery

Gene ID/ Accession	Gene name	Fold change Con vs Acu	Molecular function/ biological process
Fgfr4 Q498D6	Fibroblast growth factor receptor 4	3.32	Growth factor receptor/ proliferation
Hpse Q71RP1	Heparanase	2.75	Endoglycosidase/ cell adhesion
Itgb3 Q8R2H2	Integrin, beta 3	2.45	Receptor protein/ cell adhesion, angiogenesis

Accession numbers and molecular function/biological process obtained from UniProtKB database