Table 4.
Metastasis-associated genes that displayed significant changes in expression after Rep stress (but not Acu)
| Gene ID/ Accession | Gene name | Fold change Con vs Rep |
Molecular function/biological process |
|---|---|---|---|
| Ccl7 Q9QXY8 | Chemokine (C-C motif) ligand 7 | 11.00 | Cytokine/immune function (chemotaxis) |
| Il1b Q63264 | Interleukin 1 beta | 3.84 | Cytokine/immune function (inflammation) |
| Plaur P49616 | Plasminogen activator, urokinase receptor | 6.63 | Transmembrane protein/differentiation |
| Src Q9WUD9 | V-src sarcoma | 1.93 | Non-receptor tyrosine kinase/proliferation |
| Tp53* P10361 | Tumor protein p53 | 0.50 | Transcription factor/DNA repair, apoptosis |
Italicized text denotes genes that remained significantly changed after recovery. Only one gene was found to have downregulated expression (asterisk); bold text denotes genes identified as proto-oncogenes; bold and italicized text denotes tumor suppressor genes. Accession numbers and molecular function/biological process obtained from UniProtKB database