Table 1. Generation of GPC6-null mice.
Genotype | Number of mice | Expected frequency (%) | Observed frequency (%) |
---|---|---|---|
WT | 38 | 25 | 21.5 |
Heterozygote | 91 | 50 | 51.4 |
KO | 48 | 25 | 27.1 |
Breeding data (female Gpc6+/− × male Gpc6+/−) corresponding to 23 litters. A total of 177 embryos were collected at E17.5–E18.5.