Table 2. Univariate and multivariate analyses for overall survival in patients with bladder cancer.

Variables	Univariate analysis			Multivariate analysis
	Hazard ratio	95 % CI	p value	Hazard ratio	95 % CI	p value
Age (> 65y vs. ≤ 65y)	1.27	0.69–2.35	0.44
Gender (male vs. female)	0.52	0.19–1.47	0.22
Multifocality (multifocal vs. unifocal)	1.28	0.69–2.38	0.42
Tumor size (> 3 cm vs. ≤ 3 cm)	0.73	0.39–1.36	0.32
Stage (T2–4 vs. Ta-1)	4.49	2.08–9.71	< 0.001	5.21	1.78–15.31	< 0.001
Grade (high vs. low)	3.74	1.87–7.87	< 0.001	2.29	1.14–4.16	0.008
Recurrence (yes vs.no)	2.05	1.53–3.13	0.007	1.64	0.87–3.11	0.13
Kindlin-2 expression (high vs. low)	2.86	1.57–5.23	< 0.001	1.73	1.22–2.43	0.026
Stromal fibroblasts number (high vs. low)	1.22	0.93–1.59	0.18

Abbreviations: CI: confidence interval.