Table 1. Characteristics of eligible studies.

First Author	Year	Origin	Median age	Cases	Counting method	Definition of CD147 positive	Survival results	HR	follow-up time (month)	NOS score
Jin, J S[23]	2006	Taiwan	N	79	POSITIVE CELL PERCENTAGE*STAINING INTENSITY	>0% or weak intensity	OS	Univariate	70	7
Kim, Y[19]	2015	Korea	58	180	POSITIVE CELL PERCENTAGE*STAINING INTENSITY	>0% or weak intensity	OS	Univariate	173	7
Liang, Y X[22]	2009	China	63.5	53	STAINING INTENSITY	Brown	OS	Univariate	12	8
Rabien, A[16]	2013	Germany	60	394	POSITIVE CELL PERCENTAGE*STAINING INTENSITY	>0% or weak intensity	OS	Univariate	194	8
Tsai, W C[18]	2007	Taiwan	N	93	POSITIVE CELL PERCENTAGE*STAINING INTENSITY	>5% or weak intensity	OS	Univariate	70	7
Liu Z[24]	2007	China	53	80	POSITIVE CELL PERCENTAGE*STAINING INTENSITY	>0% or weak intensity	OS	Univariate	87	7
Ke M[17]	2013	China	51.2	82	STAINING INTENSITY	Brown	N	N	N	7
Wang SC[20]	2011	China	56.3	107	STAINING INTENSITY	Brown	N	N	N	8
Luo HR[15]	2016	China	56.3	85	STAINING INTENSITY	Brown	N	N	N	7
Chen YB[26]	2010	China	51.8	43	STAINING INTENSITY	Brown	N	N	N	7
Ma Y[25]	2009	China	58	50	PCR	N	N	N	N	7

positive cell percentage: 0 point for positive cell percentage≤ 25%;1 point for 26%-50%; 2 points for 51%-75%;3 points for>75%.; Staining intensity: 0 point for basically no coloration, 1 point for light yellow, 2 points for pale brown, and 3points for dark brown; N: not mention; OS: overall survival;