Table 3. Multivariate Cox regression analysis of recurrence and overall survivals.

		Overall survival		Recurrence-free probability
Characteristic	n	RR (95% CI)	P value	RR (95% CI)	P value
pT stage			0.164*		0.128*
pT1	10	1.00		1.00
pT2	22	3.62 (0.51–13.19)	0.349	4.17 (0.58–16.95)	0.274
pT3	55	5.76 (0.94–16.12)	0.097	6.16 (0.91–19.92)	0.090
pT4	8	5.15 (0.77–27.71)	0.105	8.73 (0.84–20.87)	0.075
pN stage			0.101†		0.095†
pN0	45	1.00		1.00
pN1	28	1.97 (0.75–8.19)	0.184	2.26 (0.85–6.37)	0.159
pN2	22	4.18 (0.89–14.42)	0.077	5.82 (0.98–16.75)	0.057
Liver metastasis
Present	78	1.00		1.00
Absent	17	1.91 (1.18–3.26)	0.025	2.15 (1.28–4.91)	0.017
CBS methylation
HPM group	42	1.00		1.00
LPM group	53	1.35 (1.09–2.41)	0.027	1.54 (1.18–3.02)	0.021

*Overall P value for pT stage.

†Overall P value for pN stage.

95% CI, 95% confidence interval; RR, risk ratio.