Table 2. Characteristic of apoptosis and autophagy in HCT116 cells and HCT-8/5-FU cells.
Groups | HCT116 cells (%) | HCT-8/5-FU cells (%) | ||
---|---|---|---|---|
Apoptosis | Autophagy | Apoptosis | Autophagy | |
Control | 4.01±0.98 | 7.21±1.64 | 3.15±0.95 | 14.52±2.88 |
5-FU | 24.15±3.14* | 44.02±9.70* | 12.25±3.54# | 50.15±10.75* |
DTN | 23.14±3.85* | 34.12±11.25* | 16.47±4.17* | 38.41±12.33* |
DHA | 16.55±2.78* | 14.76±3.08 | 15.34±2.74* | 16.24±5.45 |
5-FU+DTN | 46.62±7.46* | 41.01±10.28* | 42.68±4.37* | 47.03±11.45* |
5-FU+DHA | 43.52±8.94* | 30.14±4.66* | 40.69±6.85* | 32.15±5.88* |
DTN+DHA | 31.26±6.28* | 18.54±4.95 | 30.14±5.95* | 20.14±7.65 |
5-FU+DTN+DHA | 55.02±10.44* | 23.80±3.87 | 54.24±12.33* | 28.15±6.67 |
Notes: Data was showed aspercent (%), n = 3, *P <0.05 showed a significant difference compared to control group. # P <0.05 showed a significant difference between HCT116 cells and HCT-8/5-FU cells.,