Table 3. Genotype and allele frequencies of the HAMP gene in controls and patients with Kawasaki disease.
| Genotype | Case (%) (n =381) | Control cohort 1 (%) (n= 497) | Control cohort 2 (%) (n =500) | Cohort 1 Recessive P Value | Allelic P Value | Cohort 2 Recessive P Value | Allelic P Value | |
|---|---|---|---|---|---|---|---|---|
| rs916145 | CC | 46 (13.1) | 60 (12.2) | 71 (14.2) | 0.7108 | 0.6652 | 0.6481 | 0.4768 |
| CG | 158 (45.0) | 219 (44.7) | 231 (46.2) | |||||
| GG | 147 (41.9) | 211 (43.1) | 198 (39.6) | |||||
| rs10421768 | GG | 0 (0.0) | 0 (0.0) | 0 (0.0) | 1.0000 | 0.3270 | 1.000 | 0.4533 |
| AG | 3 (0.8) | 8 (1.6) | 7 (1.4) | |||||
| AA | 354 (99.2) | 489 (98.4) | 493 (98.6) | |||||
| rs3817623 | TT | 2 (0.6) | 2 (0.5) | 1 (0.2) | 0.8828 | 0.3129 | 03745 | 0.9983 |
| GT | 30 (8.5) | 45 (11.0) | 46 (9.2) | |||||
| GG | 322 (90.9) | 363 (88.5) | 453 (90.6) | |||||
| rs7251432 | GG | 67 (18.8) | 77 (16.1) | 67 (13.4) | 0.3120 | 0.1672 | 0.0315* | 0.0939 |
| AG | 163 (45.8) | 212 (44.5) | 243 (48.6) | |||||
| AA | 126 (35.4) | 188 (39.4) | 190 (38.0) | |||||
| rs2293689 | TT | 2 (0.6) | 4 (1.3) | 2 (0.4) | 0.3333 | 0.0410* | 0.7366 | 0.8016 |
| CT | 44 (12.3) | 54 (17.0) | 60 (12.0) | |||||
| CC | 312 (87.1) | 260 (81.7) | 438 (87.6) |
*Significant (P < 0.05) values are in bold.