Table 6. Genotype and allele frequencies of the HAMP gene in Kawasaki disease patients that respond or do not respond to intravenous immunoglobulin treatment.
| Genotype | Resistant (%) (n = 49) | Responsive (%) (n = 326) | Allele | Resistant (%) (n = 49) | Responsive (%) (n = 326) | Genotype p-value | Dominant p-value | Recessive p-value | Allelic p-value | |
|---|---|---|---|---|---|---|---|---|---|---|
| rs916145 | CC | 5 (10.6) | 40 (13.2) | C | 36 (38.3) | 212 (35.1) | 0.3306 | 0.2444 | 0.6199 | 0.5467 |
| CG | 26 (55.3) | 132 (43.7) | G | 58 (61.7) | 392 (64.9) | |||||
| GG | 16 (34.0) | 130 (43.1) | ||||||||
| rs10421768 | GG | 0 (0.0) | 0 (0.0) | G | 0 (0.0) | 3 (0.5) | - | 0.5068 | - | 0.5077 |
| AG | 0 (0.0) | 3 (1.0) | A | 45 (100.0) | 615 (99.5) | |||||
| AA | 45 (100.0) | 306 (99.0) | ||||||||
| rs3817623 | TT | 0 (0.0) | 2 (0.7) | T | 6 (6.4) | 28 (4.6) | 0.4642 | 0.3464 | 0.5777 | 0.4504 |
| GT | 6 (12.8) | 24 (7.9) | G | 88 (93.6) | 582 (95.4) | |||||
| GG | 41 (87.2) | 279 (91.5) | ||||||||
| rs7251432 | GG | 7 (15.2) | 60 (19.5) | G | 37 (40.2) | 258 (41.9) | 0.7292 | 0.9020 | 0.4911 | 0.7624 |
| AG | 23 (50.0) | 138 (44.8) | A | 55 (59.8) | 358 (58.1) | |||||
| AA | 16 (34.8) | 110 (35.7) | ||||||||
| rs2293689 | TT | 0 (0.0) | 2 (0.7) | T | 7 (7.3) | 41 (6.7) | 0.7618 | 0.7184 | 0.5749 | 0.8236 |
| CT | 7 (14.6) | 37 (12.0) | C | 89 (92.7) | 573 (93.3) | |||||
| CC | 41 (85.4) | 268 (87.3) |