Table 3.
Deep gray matter data: scan-rescan reliability (within group and field strengths)
| MS (n = 14) | NC (n = 15) | |||
|---|---|---|---|---|
| 1.5T ICC (95% CI) | 3T ICC (95% CI) | 1.5T ICC (95% CI) | 3T ICC (95% CI) | |
| Volumes | ||||
| -Thalamus | 0.99 (0.96, 1.00) | 0.99 (0.98, 1.00) | 0.95 (0.87, 0.98) | 0.99 (0.97, 1.00) |
| -Caudate | 0.99 (0.98, 1.00) | 0.99 (0.98, 1.00) | 0.97 (0.93, 0.99) | 0.96 (0.88, 0.98) |
| -Putamen | 0.94 (0.85, 0.98) | 0.97 (0.90, 0.99) | 0.95 (0.87, 0.98) | 0.97 (0.93, 0.99) |
| -Globus pallidus | 0.94 (0.83, 0.98) | 0.98 (0.95, 0.99) | 0.95 (0.87, 0.98) | 0.98 (0.93, 0.99) |
| -Total DGM | 0.99 (0.97, 1.00) | 1.00 (0.99, 1.00) | 0.98 (0.94, 0.99) | 0.99 (0.98, 1.00) |
| Fractions | ||||
| -Thalamus | 0.98 (0.95, 0.99) | 0.95 (0.87, 0.98) | 0.88 (0.71, 0.96) | 0.93 (0.81, 0.97) |
| -Caudate | 0.98 (0.94, 0.99) | 0.94 (0.84, 0.98) | 0.96 (0.88, 0.98) | 0.88 (0.69, 0.95) |
| -Putamen | 0.92 (0.78, 0.97) | 0.92 (0.78, 0.97) | 0.93 (0.81, 0.97) | 0.95 (0.86, 0.98) |
| -Globus pallidus | 0.93 (0.80, 0.97) | 0.95 (0.85, 0.98) | 0.93 (0.81, 0.97) | 0.85 (0.63, 0.94) |
| -Total DGM | 0.98 (0.93, 0.99) | 0.93 (0.80, 0.97) | 0.94 (0.84, 0.98) | 0.89 (0.72, 0.96) |
| Normalized | ||||
| -Thalamus | 0.95 (0.87, 0.98) | 0.99 (0.96, 0.99) | 0.96 (0.89, 0.99) | 0.96 (0.88, 0.98) |
| -Caudate | 0.97 (0.90, 0.99) | 0.98 (0.95, 0.99) | 0.97 (0.93, 0.99) | 0.92 (0.78, 0.97) |
| -Putamen | 0.94 (0.83, 0.98) | 0.97 (0.92, 0.99) | 0.93 (0.81, 0.97) | 0.95 (0.86, 0.98) |
| -Globus pallidus | 0.92 (0.77, 0.97) | 0.97 (0.92, 0.99) | 0.97 (0.92, 0.99) | 0.93 (0.82, 0.98) |
| -Total DGM | 0.95 (0.87, 0.98) | 0.98 (0.95, 0.99) | 0.97 (0.93, 0.99) | 0.95 (0.85, 0.98) |
Key: MS multiple sclerosis, NC normal controls, DGM cerebral subcortical deep gray matter, CI confidence interval, ICC intraclass correlation coefficient; normalized = raw volume multiplied by SIENAX normalization factor